Inhibition of γ-secretase induces G2/M arrest and triggers apoptosis in renal cell carcinoma

The present study was performed to explore the effects of Notch pathway inhibition on the proliferation and apoptosis of renal carcinoma cells. The expression levels of Notch1 and Jagged1 were examined by western blot analysis and immunohistochemistry in pathologically identified clear cell renal ce...

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Bibliographic Details
Main Authors: WU, KERONG, ZHANG, LI, LIN, YIWEI, YANG, KAI, CHENG, YUE
Format: Online
Language:English
Published: D.A. Spandidos 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063651/