An exo-cell assay for examining real-time γ-secretase activity and inhibition
γ-Secretase is an aspartyl protease that cleaves multiple substrates that are involved in broad biological processes ranging from stem cell development to neurodegeneration. The investigation of γ-secretase has been limited by currently available assays that require genetic or biochemical manipulati...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2009
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224971/ |