Beyond T and DHT - Novel Steroid Derivatives Capable of Wild Type Androgen Receptor Activation
While androgen deprivation therapy (ADT) remains the primary treatment for metastatic prostate cancer (PCa), castration does not eliminate androgens from the prostate tumor microenvironment, and residual intratumoral androgens are implicated in nearly every mechanism by which androgen receptor (AR)-...
Main Author: | Mostaghel, Elahe A |
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Format: | Online |
Language: | English |
Published: |
Ivyspring International Publisher
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062953/ |
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