Beyond T and DHT - Novel Steroid Derivatives Capable of Wild Type Androgen Receptor Activation

While androgen deprivation therapy (ADT) remains the primary treatment for metastatic prostate cancer (PCa), castration does not eliminate androgens from the prostate tumor microenvironment, and residual intratumoral androgens are implicated in nearly every mechanism by which androgen receptor (AR)-...

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Bibliographic Details
Main Author: Mostaghel, Elahe A
Format: Online
Language:English
Published: Ivyspring International Publisher 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062953/