Metabolic memory of ß-cells controls insulin secretion and is mediated by CaMKIIa

Metabolic memory of ß-cells controls insulin secretion and is mediated by CaMKIIa

Ca2+/calmodulin-dependent protein kinase II (CaMKII) functions both in regulation of insulin secretion and neurotransmitter release through common downstream mediators. Therefore, we hypothesized that pancreatic ß-cells acquire and store the information contained in calcium pulses as a form of “meta...

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Bibliographic Details
Main Authors: Santos, Gustavo Jorge dos, Ferreira, Sandra Mara, Ortis, Fernanda, Rezende, Luiz Fernando, Li, Chengyang, Naji, Ali, Carneiro, Everardo Magalhães, Kaestner, Klaus H., Boschero, Antonio Carlos
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060215/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060215/

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