Direct Activation of ATM by Resveratrol under Oxidizing Conditions

Resveratrol has been widely reported to reduce cancer progression in model systems and to selectively induce cell death in transformed cell lines. Many enzymes have been reported to respond to resveratrol in mammalian cells, including the Ataxia-Telangiectasia Mutated (ATM) protein kinase that acts...

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Bibliographic Details
Main Authors: Lee, Ji-Hoon, Guo, Zhi, Myler, Logan R., Zheng, Suting, Paull, Tanya T.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059639/