Large scale analysis of signal reachability

Motivation: Major disorders, such as leukemia, have been shown to alter the transcription of genes. Understanding how gene regulation is affected by such aberrations is of utmost importance. One promising strategy toward this objective is to compute whether signals can reach to the transcription fac...

Full description

Bibliographic Details
Main Authors: Todor, Andrei, Gabr, Haitham, Dobra, Alin, Kahveci, Tamer
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058948/