Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms

Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms

To increase our understanding of psoriasis, we utilized RNA-seq to assay the transcriptomes of lesional psoriatic and normal skin. We sequenced polyadenylated RNA-derived cDNAs from 92 psoriatic and 82 normal punch biopsies, generating an average of ~38 million single-end 80-bp reads per sample. Com...

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Bibliographic Details
Main Authors: Li, Bingshan, Tsoi, Lam C., Swindell, William R., Gudjonsson, Johann E., Tejasvi, Trilokraj, Johnston, Andrew, Ding, Jun, Stuart, Philip E., Xing, Xianying, Kochkodan, James J., Voorhees, John J., Kang, Hyun M., Nair, Rajan P., Abecasis, Goncalo R., Elder, James T.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057954/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057954/

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