RNase-mediated protein footprint sequencing reveals protein-binding sites throughout the human transcriptome

RNase-mediated protein footprint sequencing reveals protein-binding sites throughout the human transcriptome

Although numerous approaches have been developed to map RNA-binding sites of individual RNA-binding proteins (RBPs), few methods exist that allow assessment of global RBP–RNA interactions. Here, we describe PIP-seq, a universal, high-throughput, ribonuclease-mediated protein footprint sequencing app...

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Bibliographic Details
Main Authors: Silverman, Ian M, Li, Fan, Alexander, Anissa, Goff, Loyal, Trapnell, Cole, Rinn, John L, Gregory, Brian D
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053792/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053792/

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