Identification of Beta-2 as a Key Cell Adhesion Molecule in PCa Cell Neurotropic Behavior: A Novel Ex Vivo and Biophysical Approach

Prostate cancer (PCa) is believed to metastasize through the blood/lymphatics systems; however, PCa may utilize the extensive innervation of the prostate for glandular egress. The interaction of PCa and its nerve fibers is observed in 80% of PCa and is termed perineural invasion (PNI). PCa cells hav...

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Bibliographic Details
Main Authors: Jansson, Keith H., Castillo, Deborah G., Morris, Joseph W., Boggs, Mary E., Czymmek, Kirk J., Adams, Elizabeth L., Schramm, Lawrence P., Sikes, Robert A.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043823/