A Biophysical Model of Cell Adhesion Mediated by Immunoadhesin Drugs and Antibodies

A promising direction in drug development is to exploit the ability of natural killer cells to kill antibody-labeled target cells. Monoclonal antibodies and drugs designed to elicit this effect typically bind cell-surface epitopes that are overexpressed on target cells but also present on other cell...

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Bibliographic Details
Main Authors: Gutenkunst, Ryan N., Coombs, Daniel, Starr, Toby, Dustin, Michael L., Goldstein, Byron
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100730/