Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells

Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells

In mammals, the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II consists of 52 conserved heptapeptide repeats containing the consensus sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Post-translational modifications of the CTD coordinate the transcription cycle and various steps of mRNA matura...

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Bibliographic Details
Main Authors: Descostes, Nicolas, Heidemann, Martin, Spinelli, Lionel, Schüller, Roland, Maqbool, Muhammad Ahmad, Fenouil, Romain, Koch, Frederic, Innocenti, Charlène, Gut, Marta, Gut, Ivo, Eick, Dirk, Andrau, Jean-Christophe
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042876/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042876/

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