High Throughput Mutagenesis for Identification of Residues Regulating Human Prostacyclin (hIP) Receptor Expression and Function

High Throughput Mutagenesis for Identification of Residues Regulating Human Prostacyclin (hIP) Receptor Expression and Function

The human prostacyclin receptor (hIP receptor) is a seven-transmembrane G protein-coupled receptor (GPCR) that plays a critical role in vascular smooth muscle relaxation and platelet aggregation. hIP receptor dysfunction has been implicated in numerous cardiovascular abnormalities, including myocard...

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Bibliographic Details
Main Authors: Bill, Anke, Rosethorne, Elizabeth M., Kent, Toby C., Fawcett, Lindsay, Burchell, Lynn, van Diepen, Michiel T., Marelli, Anthony, Batalov, Sergey, Miraglia, Loren, Orth, Anthony P., Renaud, Nicole A., Charlton, Steven J., Gosling, Martin, Gaither, L. Alex, Groot-Kormelink, Paul J.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041722/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041722/

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