IP receptor-dependent activation of PPARγ by stable prostacyclin analogues

Stable prostacyclin analogues can signal through cell surface IP receptors or by ligand binding to nuclear peroxisome proliferator-activated receptors (PPARs). So far these agents have been reported to activate PPARα and PPARδ but not PPARγ. Given PPARγ agonists and prostacyclin analogues both inhib...

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Bibliographic Details
Main Authors: Falcetti, Emilia, Flavell, David M., Staels, Bart, Tinker, Andrew, Haworth, Sheila. G., Clapp, Lucie H.
Format: Online
Language:English
Published: Academic Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1997304/