Small molecule compounds targeting the p53 pathway: are we finally making progress?
Loss of function of p53, either through mutations in the gene or through mutations to other members of the pathway that inactivate wild-type p53, remains a critically important aspect of human cancer development. As such, p53 remains the most commonly mutated gene in human cancer. For these reasons...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Springer US
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039992/ |