Metabolic States Following Accumulation of Intracellular Aggregates: Implications for Neurodegenerative Diseases

by Vazquez, Alexei
Published 2013

Optimization of personalized therapies for anticancer treatment

by Vazquez, Alexei
Published 2013

Molecular Crowding Defines a Common Origin for the Warburg Effect in Proliferating Cells and the Lactate Threshold in Muscle Physiology

by Vazquez, Alexei, Oltvai, Zoltán N.
Published 2011

Macromolecular crowding explains overflow metabolism in cells

by Vazquez, Alexei, Oltvai, Zoltán N.
Published 2016

Mathematical models of cancer metabolism

by Markert, Elke Katrin, Vazquez, Alexei
Published 2015

Genome-wide associations of signaling pathways in glioblastoma multiforme

by Wuchty, Stefan, Vazquez, Alexei, Bozdag, Serdar
Published 2013

Inference of synergy/antagonism between anticancer drugs from the pooled analysis of clinical trials

by Kang, Wenfeng, DiPaola, Robert S, Vazquez, Alexei
Published 2013

Serine Biosynthesis with One Carbon Catabolism and the Glycine Cleavage System Represents a Novel Pathway for ATP Generation

by Vazquez, Alexei, Markert, Elke K., Oltvai, Zoltán N.
Published 2011

Small molecule compounds targeting the p53 pathway: are we finally making progress?

by Yu, Xin, Narayanan, Sumana, Vazquez, Alexei, Carpizo, Darren R.
Published 2014

Carbon catabolite repression correlates with the maintenance of near invariant molecular crowding in proliferating E. coli cells

by Zhou, Yi, Vazquez, Alexei, Wise, Aaron, Warita, Tomoko, Warita, Katsuhiko, Bar-Joseph, Ziv, Oltvai, Zoltán N
Published 2013

Cell proliferation and tissue remodeling are major determinants of cancer metabolism and the response to drugs targeting metabolism

by Markert, Elke, Tedeschi, Philip, Dolphi, Sonia, Hirshfield, Kim, Bertino, Joseph, Oltvai, Zoltan, Vazquez, Alexei
Published 2014

Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity

by Cicchini, Michelle, Chakrabarti, Rumela, Kongara, Sameera, Price, Sandy, Nahar, Ritu, Lozy, Fred, Zhong, Hua, Vazquez, Alexei, Kang, Yibin, Karantza, Vassiliki
Published 2014

Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion

by Warita, Katsuhiko, Warita, Tomoko, Beckwitt, Colin H., Schurdak, Mark E., Vazquez, Alexei, Wells, Alan, Oltvai, Zoltán N.
Published 2014

ERBB2 overexpression suppresses stress-induced autophagy and renders ERBB2-induced mammary tumorigenesis independent of monoallelic Becn1 loss

by Lozy, Fred, Cai-McRae, Xiaofeng, Teplova, Irina, Price, Sandy, Reddy, Anupama, Bhanot, Gyan, Ganesan, Shridar, Vazquez, Alexei, Karantza, Vassiliki
Published 2014

Quantification of folate metabolism using transient metabolic flux analysis

by Tedeschi, Philip M, Johnson-Farley, Nadine, Lin, Hongxia, Shelton, Laura M, Ooga, Takushi, Mackay, Gillian, Van Den Broek, Niels, Bertino, Joseph R, Vazquez, Alexei
Published 2015

The metabolic demands of cancer cells are coupled to their size and protein synthesis rates

by Dolfi, Sonia C, Chan, Leo Li-Ying, Qiu, Jean, Tedeschi, Philip M, Bertino, Joseph R, Hirshfield, Kim M, Oltvai, Zoltán N, Vazquez, Alexei
Published 2013

Metabotropic Glutamate Receptor 1 Expression and Its Polymorphic Variants Associate with Breast Cancer Phenotypes

by Mehta, Madhura S., Dolfi, Sonia C., Bronfenbrener, Roman, Bilal, Erhan, Chen, Chunxia, Moore, Dirk, Lin, Yong, Rahim, Hussein, Aisner, Seena, Kersellius, Romona D., Teh, Jessica, Chen, Suzie, Toppmeyer, Deborah L., Medina, Dan J., Ganesan, Shridar, Vazquez, Alexei, Hirshfield, Kim M.
Published 2013

Serine one-carbon catabolism with formate overflow

by Meiser, Johannes, Tumanov, Sergey, Maddocks, Oliver, Labuschagne, Christiaan Fred, Athineos, Dimitris, Van Den Broek, Niels, Mackay, Gillian M., Gottlieb, Eyal, Blyth, Karen, Vousden, Karen, Kamphorst, Jurre J., Vazquez, Alexei
Published 2016

Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis

by Cardaci, Simone, Zheng, Liang, MacKay, Gillian, van den Broek, Niels J.F., MacKenzie, Elaine D., Nixon, Colin, Stevenson, David, Tumanov, Sergey, Bulusu, Vinay, Kamphorst, Jurre J., Vazquez, Alexei, Fleming, Stewart, Schiavi, Francesca, Kalna, Gabriela, Blyth, Karen, Strathdee, Douglas, Gottlieb, Eyal
Published 2015

Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers

by Hirshfield, Kim M., Tolkunov, Denis, Zhong, Hua, Ali, Siraj M., Stein, Mark N., Murphy, Susan, Vig, Hetal, Vazquez, Alexei, Glod, John, Moss, Rebecca A., Belyi, Vladimir, Chan, Chang S., Chen, Suzie, Goodell, Lauri, Foran, David, Yelensky, Roman, Palma, Norma A., Sun, James X., Miller, Vincent A., Stephens, Philip J., Ross, Jeffrey S., Kaufman, Howard, Poplin, Elizabeth, Mehnert, Janice, Tan, Antoinette R., Bertino, Joseph R., Aisner, Joseph, DiPaola, Robert S., Rodriguez-Rodriguez, Lorna, Ganesan, Shridar
Published 2016