Wavelet Cross-Correlation to Investigate Regional Variations in Cerebral Oxygenation in Infants Supported on Extracorporeal Membrane Oxygenation
Extracorporeal membrane oxygenation can potentially affect cerebral blood flow dynamics and consequently influence cerebral autoregulation. We applied wavelet cross-correlation (WCC) between multichannel cerebral oxyhemoglobin concentration (HbO2) and mean arterial pressure (MAP), to assess regional...
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| Format: | Online |
| Language: | English |
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Springer New York
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038005/ |
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pubmed-40380052014-06-02 Wavelet Cross-Correlation to Investigate Regional Variations in Cerebral Oxygenation in Infants Supported on Extracorporeal Membrane Oxygenation Papademetriou, Maria Tachtsidis, Ilias Elliott, Martin J. Hoskote, Aparna Elwell, Clare E. Article Extracorporeal membrane oxygenation can potentially affect cerebral blood flow dynamics and consequently influence cerebral autoregulation. We applied wavelet cross-correlation (WCC) between multichannel cerebral oxyhemoglobin concentration (HbO2) and mean arterial pressure (MAP), to assess regional variations in cerebral autoregulation. Six infants on veno-arterial (VA) ECMO were studied during sequential changes in the ECMO flows. WCC between MAP and HbO2 for each flow period and each channel was calculated within three different frequency (wavelet scale) bands centered around 0.1, 0.16, and 0.3 Hz chosen to represent low frequency oscillations, ventilation, and respiration rates, respectively. The group data showed a relationship between maximum WCC and ECMO flow. During changes in ECMO flow, statistically significant differences in maximum WCC were found between right and left hemispheres. WCC between HbO2 and MAP provides a useful method to investigate the dynamics of cerebral autoregulation during ECMO. Manipulations of ECMO flows are associated with regional changes in cerebral autoregulation which may potentially have an important bearing on clinical outcome. Springer New York 2012-07-21 /pmc/articles/PMC4038005/ /pubmed/22879034 http://dx.doi.org/10.1007/978-1-4614-4989-8_28 Text en © The Author(s) 2013 |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Papademetriou, Maria Tachtsidis, Ilias Elliott, Martin J. Hoskote, Aparna Elwell, Clare E. |
| spellingShingle |
Papademetriou, Maria Tachtsidis, Ilias Elliott, Martin J. Hoskote, Aparna Elwell, Clare E. Wavelet Cross-Correlation to Investigate Regional Variations in Cerebral Oxygenation in Infants Supported on Extracorporeal Membrane Oxygenation |
| author_facet |
Papademetriou, Maria Tachtsidis, Ilias Elliott, Martin J. Hoskote, Aparna Elwell, Clare E. |
| author_sort |
Papademetriou, Maria |
| title |
Wavelet Cross-Correlation to Investigate Regional Variations
in Cerebral Oxygenation in Infants Supported on Extracorporeal Membrane
Oxygenation |
| title_short |
Wavelet Cross-Correlation to Investigate Regional Variations
in Cerebral Oxygenation in Infants Supported on Extracorporeal Membrane
Oxygenation |
| title_full |
Wavelet Cross-Correlation to Investigate Regional Variations
in Cerebral Oxygenation in Infants Supported on Extracorporeal Membrane
Oxygenation |
| title_fullStr |
Wavelet Cross-Correlation to Investigate Regional Variations
in Cerebral Oxygenation in Infants Supported on Extracorporeal Membrane
Oxygenation |
| title_full_unstemmed |
Wavelet Cross-Correlation to Investigate Regional Variations
in Cerebral Oxygenation in Infants Supported on Extracorporeal Membrane
Oxygenation |
| title_sort |
wavelet cross-correlation to investigate regional variations
in cerebral oxygenation in infants supported on extracorporeal membrane
oxygenation |
| description |
Extracorporeal membrane oxygenation can potentially affect cerebral blood flow
dynamics and consequently influence cerebral autoregulation. We applied wavelet
cross-correlation (WCC) between multichannel cerebral oxyhemoglobin concentration
(HbO2) and mean arterial pressure (MAP), to assess regional
variations in cerebral autoregulation. Six infants on veno-arterial (VA) ECMO were
studied during sequential changes in the ECMO flows. WCC between MAP and
HbO2 for each flow period and each channel was calculated
within three different frequency (wavelet scale) bands centered around 0.1, 0.16, and
0.3 Hz chosen to represent low frequency oscillations, ventilation, and respiration
rates, respectively. The group data showed a relationship between maximum WCC and ECMO
flow. During changes in ECMO flow, statistically significant differences in maximum
WCC were found between right and left hemispheres. WCC between
HbO2 and MAP provides a useful method to investigate the
dynamics of cerebral autoregulation during ECMO. Manipulations of ECMO flows are
associated with regional changes in cerebral autoregulation which may potentially have
an important bearing on clinical outcome. |
| publisher |
Springer New York |
| publishDate |
2012 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038005/ |
| _version_ |
1612094441611329536 |