Cell-cycle dependent phosphorylation of yeast pericentrin regulates γ-TuSC-mediated microtubule nucleation

Budding yeast Spc110, a member of γ-tubulin complex receptor family (γ-TuCR), recruits γ-tubulin complexes to microtubule (MT) organizing centers (MTOCs). Biochemical studies suggest that Spc110 facilitates higher-order γ-tubulin complex assembly (Kollman et al., 2010). Nevertheless the molecular ba...

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Bibliographic Details
Main Authors: Lin, Tien-chen, Neuner, Annett, Schlosser, Yvonne T, Scharf, Annette ND, Weber, Lisa, Schiebel, Elmar
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034690/