Genome-wide haploinsufficiency screen reveals a novel role for γ-TuSC in spindle organization and genome stability

Genome-wide haploinsufficiency screen reveals a novel role for γ-TuSC in spindle organization and genome stability

A genome-wide approach to screen for haploinsufficient mutants that confer genome instability identified γ-TuSC genes. γ-TuSC is an important regulator in establishing the correct number and type of microtubules so that a spindle with the proper composition is assembled to maintain genome stability....

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Bibliographic Details
Main Authors: Choy, John S., O'Toole, Eileen, Schuster, Breanna M., Crisp, Matthew J., Karpova, Tatiana S., McNally, James G., Winey, Mark, Gardner, Melissa K., Basrai, Munira A.
Format: Online
Language:English
Published: The American Society for Cell Biology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756926/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756926/

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