Acid-Sensing Ion Channels and Pain

Pathophysiological conditions such as inflammation, ischemia, infection and tissue injury can all evoke pain, and each is accompanied by local acidosis. Acid sensing ion channels (ASICs) are proton-gated cation channels expressed in both central and peripheral nervous systems. Increasing evidence su...

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Bibliographic Details
Main Authors: Gu, Qihai, Lee, Lu-Yuan
Format: Online
Language:English
Published: MDPI 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033989/