Masitinib antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance

Masitinib antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance

In this in vitro study, we determined whether masitinib could reverse multidrug resistance (MDR) in cells overexpressing the ATP binding cassette subfamily G member 2 (ABCG2) transporter. Masitinib (1.25 and 2.5 μM) significantly decreases the resistance to mitoxantrone (MX), SN38 and doxorubicin in...

Full description

Bibliographic Details
Main Authors: KATHAWALA, RISHIL J., CHEN, JUN-JIANG, ZHANG, YUN-KAI, WANG, YI-JUN, PATEL, ATISH, WANG, DE-SHEN, TALELE, TANAJI T., ASHBY, CHARLES R., CHEN, ZHE-SHENG
Format: Online
Language:English
Published: D.A. Spandidos 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027943/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027943/

Similar Items