Recent advances regarding the role of ABC subfamily C member 10 (ABCC10) in the efflux of antitumor drugs

ABCC10, also known as multidrug-resistant protein 7 (MRP7), is the tenth member of the C subfamily of the ATP-binding cassette (ABC) superfamily. ABCC10 mediates multidrug resistance (MDR) in cancer cells by preventing the intracellular accumulation of certain antitumor drugs. The ABCC10 transporter...

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Bibliographic Details
Main Authors: Kathawala, Rishil J., Wang, Yi-Jun, Ashby, Charles R., Chen, Zhe-Sheng
Format: Online
Language:English
Published: Sun Yat-sen University Cancer Center 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026542/