Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA

Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA

FANCD2 and FANCI function together in the Fanconi anemia network of deoxyribonucleic acid (DNA) crosslink repair. These proteins form the dimeric ID2 complex that binds DNA and becomes monoubiquitinated upon exposure of cells to DNA crosslinking agents. The monoubiquitinated ID2 complex is thought t...

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Bibliographic Details
Main Authors: Longerich, Simonne, Kwon, Youngho, Tsai, Miaw-Sheue, Hlaing, Aye Su, Kupfer, Gary M., Sung, Patrick
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027212/

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