Current approaches to enhance CNS delivery of drugs across the brain barriers

Although many agents have therapeutic potentials for central nervous system (CNS) diseases, few of these agents have been clinically used because of the brain barriers. As the protective barrier of the CNS, the blood–brain barrier and the blood–cerebrospinal fluid barrier maintain the brain microenv...

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Bibliographic Details
Main Authors: Lu, Cui-Tao, Zhao, Ying-Zheng, Wong, Ho Lun, Cai, Jun, Peng, Lei, Tian, Xin-Qiao
Format: Online
Language:English
Published: Dove Medical Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026551/