Polymeric micelles anchored with TAT for delivery of antibiotics across the blood-brain barrier

Polymeric micelles self-assembled from cholesterol-conjugated poly(ethylene glycol) (PEG) and anchored with transcriptional activator TAT peptide (TAT-PEG-b-Col) were fabricated for delivery of antibiotics across the blood-brain barrier (BBB). Ciprofloxacin, which demonstrated a high bactericidal ef...

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Bibliographic Details
Main Authors: Liu, Lihong, Venkatraman, S., Yang, Y., Guo, K., Lu, J., He, B., Moochhala, S., Kan, L.
Format: Conference Paper
Published: 2008
Online Access:http://hdl.handle.net/20.500.11937/28321