Impaired tumor angiogenesis and VEGF-induced pathway in endothelial CD146 knockout mice

Impaired tumor angiogenesis and VEGF-induced pathway in endothelial CD146 knockout mice

CD146 is a newly identified endothelial biomarker that has been implicated in angiogenesis. Though in vitro angiogenic function of CD146 has been extensively reported, in vivo evidence is still lacking. To address this issue, we generated endothelial-specific CD146 knockout (CD146EC-KO) mice using t...

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Bibliographic Details
Main Authors: Zeng, Qiqun, Wu, Zhenzhen, Duan, Hongxia, Jiang, Xuan, Tu, Tao, Lu, Di, Luo, Yongting, Wang, Ping, Song, Lina, Feng, Jing, Yang, Dongling, Yan, Xiyun
Format: Online
Language:English
Published: Higher Education Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026419/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026419/

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