High glucose impairs the proliferation and increases the apoptosis of endothelial progenitor cells by suppression of Akt

Aims/Introduction:  Endothelial progenitor cells (EPC) play a critical role in adult vasculogenesis and vascular repair. Previous studies have described the dysfunction of EPC in diabetic patients, but the precise mechanism is still unclear. To elucidate the dysfunction of EPC in diabetic patients,...

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Main Authors: Nakamura, Nobuhisa, Naruse, Keiko, Kobayashi, Yasuko, Matsuki, Takashi, Hamada, Yoji, Nakashima, Eitaro, Kamiya, Hideki, Hata, Masaki, Nishikawa, Toru, Enomoto, Atsushi, Takahashi, Masahide, Murohara, Toyoaki, Matsubara, Tatsuaki, Oiso, Yutaka, Nakamura, Jiro
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014965/