2‐Methoxyestradiol ameliorates glucose tolerance with the increase in β‐cell mass in db/db mice

Aims/Introduction: 2‐Methoxyestradiol (2ME) is an estradiol metabolite with little estrogenic activity. Previous data identified its anti‐carcinogenic properties and possible cardiovascular benefits. However, its effect on diabetes mellitus has not been fully elucidated. The aim of the present stud...

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Main Authors:	Yorifuji, Takashi, Uchida, Toyoyoshi, Abe, Hiroko, Toyofuku, Yukiko, Tamaki, Motoyuki, Fujitani, Yoshio, Hirose, Takahisa, Kawamori, Ryuzo, Takeda, Satoru, Watada, Hirotaka
Format:	Online
Language:	English
Published:	Blackwell Publishing Ltd 2010
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014916/

id	pubmed-4014916
recordtype	oai_dc
spelling	pubmed-40149162014-05-19 2‐Methoxyestradiol ameliorates glucose tolerance with the increase in β‐cell mass in db/db mice Yorifuji, Takashi Uchida, Toyoyoshi Abe, Hiroko Toyofuku, Yukiko Tamaki, Motoyuki Fujitani, Yoshio Hirose, Takahisa Kawamori, Ryuzo Takeda, Satoru Watada, Hirotaka Articles Aims/Introduction: 2‐Methoxyestradiol (2ME) is an estradiol metabolite with little estrogenic activity. Previous data identified its anti‐carcinogenic properties and possible cardiovascular benefits. However, its effect on diabetes mellitus has not been fully elucidated. The aim of the present study was to determine the effects of 2ME on glucose metabolism in the diabetic state. Blackwell Publishing Ltd 2010-12-19 2011-06-05 /pmc/articles/PMC4014916/ /pubmed/24843481 http://dx.doi.org/10.1111/j.2040-1124.2010.00087.x Text en © 2010 Asian Association for the Study of Diabetes and Blackwell Publishing Asia Pty Ltd
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Yorifuji, Takashi Uchida, Toyoyoshi Abe, Hiroko Toyofuku, Yukiko Tamaki, Motoyuki Fujitani, Yoshio Hirose, Takahisa Kawamori, Ryuzo Takeda, Satoru Watada, Hirotaka
spellingShingle	Yorifuji, Takashi Uchida, Toyoyoshi Abe, Hiroko Toyofuku, Yukiko Tamaki, Motoyuki Fujitani, Yoshio Hirose, Takahisa Kawamori, Ryuzo Takeda, Satoru Watada, Hirotaka 2‐Methoxyestradiol ameliorates glucose tolerance with the increase in β‐cell mass in db/db mice
author_facet	Yorifuji, Takashi Uchida, Toyoyoshi Abe, Hiroko Toyofuku, Yukiko Tamaki, Motoyuki Fujitani, Yoshio Hirose, Takahisa Kawamori, Ryuzo Takeda, Satoru Watada, Hirotaka
author_sort	Yorifuji, Takashi
title	2‐Methoxyestradiol ameliorates glucose tolerance with the increase in β‐cell mass in db/db mice
title_short	2‐Methoxyestradiol ameliorates glucose tolerance with the increase in β‐cell mass in db/db mice
title_full	2‐Methoxyestradiol ameliorates glucose tolerance with the increase in β‐cell mass in db/db mice
title_fullStr	2‐Methoxyestradiol ameliorates glucose tolerance with the increase in β‐cell mass in db/db mice
title_full_unstemmed	2‐Methoxyestradiol ameliorates glucose tolerance with the increase in β‐cell mass in db/db mice
title_sort	2‐methoxyestradiol ameliorates glucose tolerance with the increase in β‐cell mass in db/db mice
description	Aims/Introduction: 2‐Methoxyestradiol (2ME) is an estradiol metabolite with little estrogenic activity. Previous data identified its anti‐carcinogenic properties and possible cardiovascular benefits. However, its effect on diabetes mellitus has not been fully elucidated. The aim of the present study was to determine the effects of 2ME on glucose metabolism in the diabetic state.
publisher	Blackwell Publishing Ltd
publishDate	2010
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014916/
_version_	1612086932042416128

2‐Methoxyestradiol ameliorates glucose tolerance with the increase in β‐cell mass in db/db mice

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