2‐Methoxyestradiol ameliorates glucose tolerance with the increase in β‐cell mass in db/db mice

Aims/Introduction:  2‐Methoxyestradiol (2ME) is an estradiol metabolite with little estrogenic activity. Previous data identified its anti‐carcinogenic properties and possible cardiovascular benefits. However, its effect on diabetes mellitus has not been fully elucidated. The aim of the present stud...

Full description

Bibliographic Details
Main Authors: Yorifuji, Takashi, Uchida, Toyoyoshi, Abe, Hiroko, Toyofuku, Yukiko, Tamaki, Motoyuki, Fujitani, Yoshio, Hirose, Takahisa, Kawamori, Ryuzo, Takeda, Satoru, Watada, Hirotaka
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014916/