Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth

Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth

Loss of secreted phospholipase A2 receptor (PLA2R1) has recently been found to render human primary cells more resistant to senescence whereas increased PLA2R1 expression is able to induce cell cycle arrest, cancer cell death or blockage of cancer cell transformation in vitro, suggesting that PLA2R1...

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Bibliographic Details
Main Authors: Vindrieux, David, Devailly, Guillaume, Augert, Arnaud, Calvé, Benjamin Le, Ferrand, Mylène, Pigny, Pascal, Payen, Léa, Lambeau, Gérard, Perrais, Michael, Aubert, Sébastien, Simonnet, Hélène, Dante, Robert, Bernard, David
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011578/

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