The Role of TPA I/D and PAI-1 4G/5G Polymorphisms in Multiple Sclerosis

The Role of TPA I/D and PAI-1 4G/5G Polymorphisms in Multiple Sclerosis

Background. Previous studies have shown impaired fibrinolysis in multiple sclerosis (MS) and implicated extracellular proteolytic enzymes as important factors in demyelinating neuroinflammatory disorders. Tissue-type plasminogen activator (t-PA) and its inhibitor (PAI-1) are key molecules in both f...

Full description

Bibliographic Details
Main Authors:	Živković, Maja, Starčević Čizmarević, Nada, Lovrečić, Luca, Klupka-Sarić, Inge, Stanković, Aleksandra, Gašparović, Iva, Lavtar, Polona, Dinčić, Evica, Stojković, Ljiljana, Rudolf, Gorazd, Šega Jazbec, Saša, Perković, Olivio, Sinanović, Osman, Sepčić, Juraj, Kapović, Miljenko, Peterlin, Borut, Ristić, Smiljana
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2014
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009184/

Similar Items

Low frequency of HFE gene mutations in Croatian patients suspected of having hereditary hemochromatosis
by: Milić, Sandra, et al.
Published: (2011)

Functional Inference of Methylenetetrahydrofolate Reductase Gene Polymorphisms on Enzyme Stability as a Potential Risk Factor for Down Syndrome in Croatia
by: Vraneković, Jadranka, et al.
Published: (2010)

The Role of Iron and Iron Overload in Chronic Liver Disease
by: Milic, Sandra, et al.
Published: (2016)

Brachytelephalangic chondrodysplasia punctata caused by new small hemizygous deletion in a boy presenting with hearing loss
by: Vrečar, Irena, et al.
Published: (2015)

Functional Polymorphisms of Matrix Metalloproteinases 1 and 9 Genes in Women with Spontaneous Preterm Birth
by: Pereza, Nina, et al.
Published: (2014)

C.35delG/ GJB2 and del(GJB6-D13S1830) mutations in Croatians with prelingual non-syndromic hearing impairment
by: Medica, Igor, et al.
Published: (2005)

Clinical utility of array comparative genomic hybridisation in prenatal setting
by: Lovrecic, Luca, et al.
Published: (2016)

Tumor necrosis factor-alpha gene promoter -308 and -238 polymorphisms in patients with lung cancer as a second primary tumor
by: Flego, Veljko, et al.
Published: (2013)

Growth and training go in tandem at TPA
Published: (2006)

Kinetically governed polymorphism of d(G4T4G3) quadruplexes in K+ solutions
by: Prislan, Iztok, et al.
Published: (2011)

Small internal jugular veins with restricted outflow are associated with severe multiple sclerosis: a sonographer-blinded, case–control ultrasound study
by: Krsmanović, Željko, et al.
Published: (2013)

Tissue polypeptide antigen (TPA) in pancreatic cancer diagnosis.
by: Panucci, A., et al.
Published: (1985)

Trading Partners Agreement Markup Language (tpaML)
by: Marilyn, Geller, et al.
Published: (2000)

Expression Signature as a Biomarker for Prenatal Diagnosis of Trisomy 21
by: Volk, Marija, et al.
Published: (2013)

Direct-to-consumer genetic testing in Slovenia: availability, ethical dilemmas and legislation
by: Vrecar, Irena, et al.
Published: (2015)

Polymorphism of the ADRB2 rs1042713 gene is not associated with spontaneous preterm birth: Analyses in a Slovenian sample and meta analysis
by: A Peterlin, et al.
Published: (2017-12-01)

Genetic variation in the CLOCK gene is associated with idiopathic recurrent spontaneous abortion.
by: Alenka Hodžić, et al.

Thermodynamic fingerprints of ligand binding to human telomeric G-quadruplexes
by: Bončina, Matjaž, et al.
Published: (2015)

Altered LINE-1 Methylation in Mothers of Children with Down Syndrome
by: Babić Božović, Ivana, et al.
Published: (2015)

A survey of TPA usage in Canada for hemodialysis central venous catheter malfunction.
by: Lam, E, et al.
Published: (2012)

Preclinical assessment of adjunctive tPA and DNase for peritoneal dialysis associated peritonitis
by: McGuire, A., et al.
Published: (2015)

Effect of TPA on ion fluxes and DNA synthesis in vascular smooth muscle cells
Published: (1985)

Intravenous tPA Therapy Does Not Worsen Acute Intracerebral Hemorrhage in Mice
by: Foerch, Christian, et al.
Published: (2013)

Variability in the Perception of Informed Consent for IV-tPA during Telestroke Consultation
by: Thomas, Lisa, et al.
Published: (2012)

Expression of uPA, tPA, and PAI-1 in Calcified Aortic Valves
by: Kochtebane, Najlah, et al.
Published: (2014)

Synergy of Combined tPA-Edaravone Therapy in Experimental Thrombotic Stroke
by: Sun, Yu-Yo, et al.
Published: (2014)

tPA Deficiency in Mice Leads to Rearrangement in the Cerebrovascular Tree and Cerebroventricular Malformations
by: Stefanitsch, Christina, et al.
Published: (2015)

Impacts of tissue-type plasminogen activator (tPA) on neuronal survival
by: Chevilley, Arnaud, et al.
Published: (2015)

Unintentional intramuscular administration of tPA/DNase for pleural infection
by: Popowicz, Natalia, et al.
Published: (2014)

Hemi Orolingual Angioedema after tPA Administration for Acute Ischemic Stroke
by: Madden, Bryan, et al.
Published: (2015)

The Heterochromatin-1 Phosphorylation Contributes to TPA-Induced AP-1 Expression
by: Choi, Won Jun
Published: (2014)

Preclinical Assessment of Adjunctive tPA and DNase for Peritoneal Dialysis Associated Peritonitis
by: McGuire, Amanda L., et al.
Published: (2015)

Characterization of Cubic Graphs G with irt(G) = Irt(G) = 2
by: Eslahchi Changiz, et al.
Published: (2014-08-01)

New approach of (G′/G)-expansion method and new approach of generalized (G′/G)-expansion method for nonlinear evolution equation
by: Hasibun Naher, et al.
Published: (2013-03-01)

d(CGGTGGT) forms an octameric parallel G-quadruplex via stacking of unusual G(:C):G(:C):G(:C):G(:C) octads
by: Borbone, Nicola, et al.
Published: (2011)

Galangin, a novel dietary flavonoid, attenuates metastatic feature via PKC/ERK signaling pathway in TPA-treated liver cancer HepG2 cells
by: Chien, Shang-Tao, et al.
Published: (2015)

Microduplication in the 2p16.1p15 chromosomal region linked to developmental delay and intellectual disability
by: Luca Lovrecic, et al.
Published: (2018-06-01)

Equivariant principal bundles for G–actions and G–connections
by: Biswas Indranil, et al.
Published: (2015-12-01)

4G or not 4G – a progress report
by: Peter, Curwen
Published: (2016)

Changes in IgG and total plasma protein glycomes in acute systemic inflammation
by: Novokmet, Mislav, et al.
Published: (2014)