Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes

Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes

The importance of understanding the molecular mechanisms of murine leukemia virus (MLV) integration into host chromatin is highlighted by the development of MLV-based vectors for human gene-therapy. We have recently identified BET proteins (Brd2, 3 and 4) as the main cellular binding partners of MLV...

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Bibliographic Details
Main Authors: Larue, Ross C., Plumb, Matthew R., Crowe, Brandon L., Shkriabai, Nikoloz, Sharma, Amit, DiFiore, Julia, Malani, Nirav, Aiyer, Sriram S., Roth, Monica J., Bushman, Frederic D., Foster, Mark P., Kvaratskhelia, Mamuka
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005663/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005663/

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