HIV-1 Integrase-DNA Recognition Mechanisms
Integration of a reverse transcribed DNA copy of the HIV viral genome into the host chromosome is essential for virus replication. This process is catalyzed by the virally encoded protein integrase. The catalytic activities, which involve DNA cutting and joining steps, have been recapitulated in vit...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Molecular Diversity Preservation International (MDPI)
2009
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185514/ |