Novel functional small RNAs are selectively loaded onto mammalian Ago1

Novel functional small RNAs are selectively loaded onto mammalian Ago1

Argonaute (Ago) proteins function in RNA silencing as components of the RNA-induced silencing complex (RISC). In lower organisms, the small interfering RNA and miRNA pathways diverge due in part to sorting mechanisms that direct distinct small RNA (sRNA) duplexes onto specific Ago-RISCs. However, su...

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Bibliographic Details
Main Authors: Yamakawa, Natsuko, Okuyama, Kazuki, Ogata, Jun, Kanai, Akinori, Helwak, Aleksandra, Takamatsu, Masako, Imadome, Ken-ichi, Takakura, Kohei, Chanda, Bidisha, Kurosaki, Natsumi, Yamamoto, Haruna, Ando, Kiyoshi, Matsui, Hirotaka, Inaba, Toshiya, Kotani, Ai
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005649/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005649/

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