Inflammatory cytokines in pulmonary hypertension

Pulmonary hypertension is an “umbrella term” used for a spectrum of entities resulting in an elevation of the pulmonary arterial pressure. Clinical symptoms include dyspnea and fatigue which in the absence of adequate therapeutic intervention may lead to progressive right heart failure and death. Th...

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Main Authors:	Groth, Alexandra, Vrugt, Bart, Brock, Matthias, Speich, Rudolf, Ulrich, Silvia, Huber, Lars C
Format:	Online
Language:	English
Published:	BioMed Central 2014
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002553/

id	pubmed-4002553
recordtype	oai_dc
spelling	pubmed-40025532014-04-29 Inflammatory cytokines in pulmonary hypertension Groth, Alexandra Vrugt, Bart Brock, Matthias Speich, Rudolf Ulrich, Silvia Huber, Lars C Review Pulmonary hypertension is an “umbrella term” used for a spectrum of entities resulting in an elevation of the pulmonary arterial pressure. Clinical symptoms include dyspnea and fatigue which in the absence of adequate therapeutic intervention may lead to progressive right heart failure and death. The pathogenesis of pulmonary hypertension is characterized by three major processes including vasoconstriction, vascular remodeling and microthrombotic events. In addition accumulating evidence point to a cytokine driven inflammatory process as a major contributor to the development of pulmonary hypertension. BioMed Central 2014 2014-04-16 /pmc/articles/PMC4002553/ /pubmed/24739042 http://dx.doi.org/10.1186/1465-9921-15-47 Text en Copyright © 2014 Groth et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Groth, Alexandra Vrugt, Bart Brock, Matthias Speich, Rudolf Ulrich, Silvia Huber, Lars C
spellingShingle	Groth, Alexandra Vrugt, Bart Brock, Matthias Speich, Rudolf Ulrich, Silvia Huber, Lars C Inflammatory cytokines in pulmonary hypertension
author_facet	Groth, Alexandra Vrugt, Bart Brock, Matthias Speich, Rudolf Ulrich, Silvia Huber, Lars C
author_sort	Groth, Alexandra
title	Inflammatory cytokines in pulmonary hypertension
title_short	Inflammatory cytokines in pulmonary hypertension
title_full	Inflammatory cytokines in pulmonary hypertension
title_fullStr	Inflammatory cytokines in pulmonary hypertension
title_full_unstemmed	Inflammatory cytokines in pulmonary hypertension
title_sort	inflammatory cytokines in pulmonary hypertension
description	Pulmonary hypertension is an “umbrella term” used for a spectrum of entities resulting in an elevation of the pulmonary arterial pressure. Clinical symptoms include dyspnea and fatigue which in the absence of adequate therapeutic intervention may lead to progressive right heart failure and death. The pathogenesis of pulmonary hypertension is characterized by three major processes including vasoconstriction, vascular remodeling and microthrombotic events. In addition accumulating evidence point to a cytokine driven inflammatory process as a major contributor to the development of pulmonary hypertension.
publisher	BioMed Central
publishDate	2014
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002553/
_version_	1612083163792670720

Inflammatory cytokines in pulmonary hypertension

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