WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells
The WASF3 gene promotes invasion and metastasis in breast cancer cells which have undergone epithelial-to-mesenchyme transition (EMT). Overexpression of WASF3 in cells that do not show EMT increases their invasion potential as a result of increased ZEB1/2 levels which specifically suppress the anti-...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998093/ |