miR-200c regulates crizotinib-resistant ALK-positive lung cancer cells by reversing epithelial-mesenchymal transition via targeting ZEB1
Crizotinib is an orally administered drug for the treatment of patients with anaplastic lymphoma kinase (ALK)-positive locally advanced or metastatic non-small cell lung cancer (NSCLC). Despite the impressive efficacy of crizotinib in the treatment of ALK-positive lung cancer, acquired resistance ev...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
D.A. Spandidos
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101903/ |