A Humanized Mouse Model of Autoimmune Insulitis

Many mechanisms of and treatments for type 1 diabetes studied in the NOD mouse model have not been replicated in human disease models. Thus, the field of diabetes research remains hindered by the lack of an in vivo system in which to study the development and onset of autoimmune diabetes. To this en...

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Bibliographic Details
Main Authors: Viehmann Milam, Ashley A., Maher, Stephen E., Gibson, Joanna A., Lebastchi, Jasmin, Wen, Li, Ruddle, Nancy H., Herold, Kevan C., Bothwell, Alfred L.M.
Format: Online
Language:English
Published: American Diabetes Association 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994947/