Immune Therapy and β-Cell Death in Type 1 Diabetes

Type 1 diabetes (T1D) results from immune-mediated destruction of insulin-producing β-cells. The killing of β-cells is not currently measurable; β-cell functional studies routinely used are affected by environmental factors such as glucose and cannot distinguish death from dysfunction. Moreover, it...

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Bibliographic Details
Main Authors: Lebastchi, Jasmin, Deng, Songyan, Lebastchi, Amir H., Beshar, Isabel, Gitelman, Stephen, Willi, Steven, Gottlieb, Peter, Akirav, Eitan M., Bluestone, Jeffrey A., Herold, Kevan C.
Format: Online
Language:English
Published: American Diabetes Association 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636605/