Optimal Translational Termination Requires C4 Lysyl Hydroxylation of eRF1

Optimal Translational Termination Requires C4 Lysyl Hydroxylation of eRF1

Efficient stop codon recognition and peptidyl-tRNA hydrolysis are essential in order to terminate translational elongation and maintain protein sequence fidelity. Eukaryotic translational termination is mediated by a release factor complex that includes eukaryotic release factor 1 (eRF1) and eRF3. T...

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Bibliographic Details
Main Authors: Feng, Tianshu, Yamamoto, Atsushi, Wilkins, Sarah E., Sokolova, Elizaveta, Yates, Luke A., Münzel, Martin, Singh, Pooja, Hopkinson, Richard J., Fischer, Roman, Cockman, Matthew E., Shelley, Jake, Trudgian, David C., Schödel, Johannes, McCullagh, James S.O., Ge, Wei, Kessler, Benedikt M., Gilbert, Robert J., Frolova, Ludmila Y., Alkalaeva, Elena, Ratcliffe, Peter J., Schofield, Christopher J., Coleman, Mathew L.
Format: Online
Language:English
Published: Cell Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991326/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991326/

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