Huntingtin Regulates Mammary Stem Cell Division and Differentiation

Little is known about the mechanisms of mitotic spindle orientation during mammary gland morphogenesis. Here, we report the presence of huntingtin, the protein mutated in Huntington’s disease, in mouse mammary basal and luminal cells throughout mammogenesis. Keratin 5-driven depletion of huntingtin...

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Bibliographic Details
Main Authors: Elias, Salah, Thion, Morgane S., Yu, Hua, Sousa, Cristovao Marques, Lasgi, Charlène, Morin, Xavier, Humbert, Sandrine
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986500/