Age-Dependent Effects of UCP2 Deficiency on Experimental Acute Pancreatitis in Mice

Age-Dependent Effects of UCP2 Deficiency on Experimental Acute Pancreatitis in Mice

Reactive oxygen species (ROS) have been implicated in the pathogenesis of acute pancreatitis (AP) for many years but experimental evidence is still limited. Uncoupling protein 2 (UCP2)-deficient mice are an accepted model of age-related oxidative stress. Here, we have analysed how UCP2 deficiency af...

Full description

Bibliographic Details
Main Authors:	Müller, Sarah, Kaiser, Hannah, Krüger, Burkhard, Fitzner, Brit, Lange, Falko, Bock, Cristin N., Nizze, Horst, Ibrahim, Saleh M., Fuellen, Georg, Wolkenhauer, Olaf, Jaster, Robert
Format:	Online
Language:	English
Published:	Public Library of Science 2014
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983280/

Similar Items

The mtDNA nt7778 G/T Polymorphism Augments Formation of Lymphocytic Foci but Does Not Aggravate Cerulein-Induced Acute Pancreatitis in Mice
by: Müller, Sarah, et al.
Published: (2014)

Parameter Identifiability and Sensitivity Analysis Predict Targets for Enhancement of STAT1 Activity in Pancreatic Cancer and Stellate Cells
by: Rateitschak, Katja, et al.
Published: (2012)

Senescence determines the fate of activated rat pancreatic stellate cells
by: Fitzner, Brit, et al.
Published: (2012)

In vitro studies implicate an imbalanced activation of dendritic cells in the pathogenesis of murine autoimmune pancreatitis
by: Borufka, Luise, et al.
Published: (2016)

Reduced Adolescent-Age Spatial Learning Ability Associated with Elevated Juvenile-Age Superoxide Levels in Complex I Mouse Mutants
by: Mayer, Johannes, et al.
Published: (2015)

Quantitative Trait Locus Analysis Implicates CD4+/CD44high Memory T Cells in the Pathogenesis of Murine Autoimmune Pancreatitis
by: Bischof, Julia, et al.
Published: (2015)

UCP-2 and UCP-3 Proteins Are Differentially Regulated in Pancreatic Beta-Cells
by: Li, Yunfeng, et al.
Published: (2008)

Anti-inflammatory effects of reactive oxygen species – a multi-valued logical model validated by formal concept analysis
by: Wollbold, Johannes, et al.
Published: (2014)

Molecular regulation of pancreatic stellate cell function
by: Jaster, Robert
Published: (2004)

Deletion of UCP2 in iNOS Deficient Mice Reduces the Severity of the Disease during Experimental Autoimmune Encephalomyelitis
by: Aheng, Caroline, et al.
Published: (2011)

Inbred mouse strains reveal biomarkers that are pro-longevity, antilongevity or role switching
by: Moeller, Mark, et al.
Published: (2014)

Polymorphisms in uncoupling protein genes UCP2 and UCP3 are not associated with HIV-associated sensory neuropathy in African individuals.
by: Wadley, A., et al.
Published: (2013)

UCP2 and UCP3 polymorphisms as risk factors of insulin resistance for Indonesian obese adolescents
by: Mexitalia, M, et al.
Published: (2013)

Erratum to: Anion Transport or Nucleotide Binding by Ucp2 Is Indispensable for Ucp2-Mediated Efferocytosis
by: Lee, Suho, et al.
Published: (2015)

Anion Transport or Nucleotide Binding by Ucp2 Is Indispensable for Ucp2-Mediated Efferocytosis
by: Lee, Suho, et al.
Published: (2015)

UCP1 and UCP3 Expression Is Associated with Lipid and Carbohydrate Oxidation and Body Composition
by: Oliveira, Bruno A. P., et al.
Published: (2016)

The role of theory and modeling in medical research
by: Wolkenhauer, Olaf
Published: (2013)

Why model?
by: Wolkenhauer, Olaf
Published: (2014)

Perforin deficiency attenuates collagen-induced arthritis
by: Bauer, Kristin, et al.
Published: (2005)

UCP2 Regulates the Glucagon Response to Fasting and Starvation
by: Allister, Emma M., et al.
Published: (2013)

When pigs fly, UCP1 makes heat
by: Jastroch, Martin, et al.
Published: (2015)

UCP 600: the new rules on documentary compliance
by: Hang, Yen Low
Published: (2010)

Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells
by: Bordone, Laura, et al.
Published: (2006)

Correction: Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic ß Cells
by: Bordone, Laura, et al.
Published: (2006)

Correction: Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells
by: Bordone, Laura, et al.
Published: (2015)

Analysis of Uncoupling Protein 2-Deficient Mice upon Anaesthesia and Sedation Revealed a Role for UCP2 in Locomotion
by: Alves-Guerra, Marie-Clotilde, et al.
Published: (2012)

UCP3 Regulates Cardiac Efficiency and Mitochondrial Coupling in High Fat–Fed Mice but Not in Leptin-Deficient Mice
by: Boudina, Sihem, et al.
Published: (2012)

UCP2 Deficiency Helps to Restrict the Pathogenesis of Experimental Cutaneous and Visceral Leishmaniosis in Mice
by: Carrión, Javier, et al.
Published: (2013)

Biological and Molecular Effects of Small Molecule Kinase Inhibitors on Low-Passage Human Colorectal Cancer Cell Lines
by: Lange, Falko, et al.
Published: (2014)

UCP2 -866G/A, Ala55Val and UCP3 -55C/T Polymorphisms in Association with Obesity Susceptibility — A Meta-Analysis Study
by: Qian, Li, et al.
Published: (2013)

Polymorphisms of the UCP2 Gene Are Associated with Glomerular Filtration Rate in Type 2 Diabetic Patients and with Decreased UCP2 Gene Expression in Human Kidney
by: de Souza, Bianca Marmontel, et al.
Published: (2015)

Morphometric Measurements to Quantify the Cerulein Induced Hyperstimulatory Pancreatitis of Rats under the Protective Effect of Lectins
by: Jonas, Ludwig, et al.
Published: (1998)

Islamic Letter of Credit (LC-i) in Malaysia: the UCP 600 and the issue of interest
by: Syed Alwi, Sharifah Faigah, et al.
Published: (2011)

The UCP 600 rules in letter of credit (LC): Selected issues
by: Che Hashim, R.
Published: (2015)

Role of UCP2 Expression after Hepatic Warm Ischemia-Reperfusion in the Rat
by: Ninomiya, Mizuki, et al.
Published: (2011)

Upregulation of UCP2 by Adiponectin: The Involvement of Mitochondrial Superoxide and hnRNP K
by: Zhou, Mingyan, et al.
Published: (2012)

New Aspects of Mitochondrial Uncoupling Proteins (UCPs) and Their Roles in Tumorigenesis
by: Robbins, Delira, et al.
Published: (2011)

Cellular stress response, sirtuins and UCP proteins in Alzheimer disease: role of vitagenes
by: Cornelius, Carolin, et al.
Published: (2013)

The UCP 600 rules in letter of credit (LC): selected issues
by: Nik Zainun
Published: (2016)

Characterization and properties of the biosurfactant produced by Candida lipolytica UCP 0988
by: Raquel Diniz Rufino, et al.
Published: (2014-01-01)