JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells

JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells

Rhabdomyosarcomas (RMS) are the most frequent soft-tissue sarcoma in children and characteristically show features of developing skeletal muscle. The alveolar subtype is frequently associated with a PAX3-FOXO1 fusion protein that is known to contribute to the undifferentiated myogenic phenotype of R...

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Bibliographic Details
Main Authors: Walters, Zoë S, Villarejo-Balcells, Barbara, Olmos, David, Buist, Thomas WS, Missiaglia, Edoardo, Allen, Rebecca, Al-Lazikani, Bissan, Garrett, Michelle D, Blagg, Julian, Shipley, Janet
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982124/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982124/

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