Prozone effects in microscopic agglutination tests for leptospirosis in the sera of mice infected with the pathogenic Leptospira interrogans serovar Canicola

Mice experimentally infected with a pathogenic strain of Leptospira interrogans serovar Canicola produced false negative results (prozone effect) in a microscopic agglutination test (MAT). This prozone effect occurred in several serum samples collected at different post-infection times, but it was m...

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Bibliographic Details
Main Authors: Shimabukuro, Fabio Hiroto, da Costa, Veruska Maia, da Silva, Rodrigo Costa, Langoni, Hélio, da Silva, Aristeu Vieira, de Carvalho, Lídia Raquel, Domingues, Paulo Francisco
Format: Online
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970589/