A key role for neuropeptide Y in lifespan extension and cancer suppression via dietary restriction

A key role for neuropeptide Y in lifespan extension and cancer suppression via dietary restriction

Knowledge of genes essential for the life-extending effect of dietary restriction (DR) in mammals is incomplete. In this study, we found that neuropeptide Y (Npy), which mediates physiological adaptations to energy deficits, is an essential link between DR and longevity in mice. The lifespan-prolong...

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Bibliographic Details
Main Authors: Chiba, Takuya, Tamashiro, Yukari, Park, Daeui, Kusudo, Tatsuya, Fujie, Ryoko, Komatsu, Toshimitsu, Kim, Sang Eun, Park, Seongjoon, Hayashi, Hiroko, Mori, Ryoichi, Yamashita, Hitoshi, Chung, Hae Young, Shimokawa, Isao
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970128/

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