The neuropeptide neuromedin U promotes inflammation by direct activation of mast cells

Neuromedin U (NMU) is a neuropeptide that is expressed in the gastrointestinal tract and central nervous system. NMU interacts with two G protein–coupled receptors, NMU-R1 and NMU-R2. Whereas NMU-R2 localizes predominantly to nerve cells, NMU-R1 is expressed in peripheral tissues including lymphocyt...

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Bibliographic Details
Main Authors: Moriyama, Maiko, Sato, Takahiro, Inoue, Hiromasa, Fukuyama, Satoru, Teranishi, Hitoshi, Kangawa, Kenji, Kano, Tatsuhiko, Yoshimura, Akihiko, Kojima, Masayasu
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213011/