Ecto-5′-Nucleotidase (CD73) Regulates Host Inflammatory Responses and Exacerbates Murine Salmonellosis

Ecto-5′-Nucleotidase (CD73) Regulates Host Inflammatory Responses and Exacerbates Murine Salmonellosis

Food-borne Salmonella spp., are a major cause of hospitalization and death. Adenosine, an important immune regulator of inflammation, limits tissue damage during infection. CD39 (nucleoside triphosphate dephosphorylase) combined with ecto-5′-nucleotidase (CD73) metabolizes ATP to adenosine. We studi...

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Bibliographic Details
Main Authors: Alam, M. Samiul, Kuo, Jennifer L., Ernst, Peter B., Derr-Castillo, Victoria, Pereira, Marion, Gaines, Dennis, Costales, Matthew, Bigley, Elmer, Williams, Kristina
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967249/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967249/

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