The volatile anesthetic isoflurane induces ecto-5′-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury

The volatile anesthetic isoflurane induces ecto-5′-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury

The volatile anesthetic isoflurane protects against renal ischemia and reperfusion injury by releasing renal tubular TGF-β1. Since adenosine is a powerful cytoprotective molecule, we tested whether TGF-β1 generated by isoflurane induces renal tubular ecto-5′-nucleotidase (CD73) and adenosine to prot...

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Bibliographic Details
Main Authors: Kim, Mihwa, Ham, Ahrom, Kim, Joo Yun, Brown, Kevin M., D’Agati, Vivette D., Lee, H. Thomas
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676468/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676468/

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