Inputs and outputs of insulin receptor
The insulin receptor (IR) is an important hub in insulin signaling and its activation is tightly regulated. Upon insulin stimulation, IR is activated through autophosphorylation, and consequently phosphorylates several insulin receptor substrate (IRS) proteins, including IRS1-6, Shc and Gab1. Certai...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Higher Education Press
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967058/ |