Prolyl-hydroxylase 3: evolving roles for an ancient signaling protein
The ability of cells to sense oxygen is a highly evolved process that facilitates adaptations to the local oxygen environment and is critical to energy homeostasis. In vertebrates, this process is largely controlled by three intracellular prolyl-4-hydroxylases (PHD) 1–3. These related enzymes share...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Dove Medical Press
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963164/ |